Tuesday, August 25, 2020

A Stock Analysis Report On Starhub Economics Essay

A Stock Analysis Report On Starhub Economics Essay The fallout of the money related emergency in the year 2008 has unfavorably influenced the monetary frameworks on the planet; causing liquidity in the credit markets to evaporate and in the end brought about numerous budgetary foundations confronting indebtedness issues. Organizations around the globe confronted intense occasions in getting assets as banks got moderate in loaning. Money related specialists around the globe in this way took gauges in an offer to control the wide spread of the emergency to decrease the effects. Singapore was not saved in the emergency as well and now observes enormous assets, money related approaches and financial plans being actualized to facilitate the circumstance. In 2009, Singapores GDP diminished by 7.5% from a development pace of 21.7% in the post-emergency ricochet Q2 to 14.2% in Q3. In any case, there were expanding indications of recuperation in Q3, demonstrating an extension of all areas in the economy. This mirrored a superior than-anticipated result for Singapores GDP development estimate for 2009 and has been amended upwards to between - 2.5% and - 2%, from - 6% to - 4%. The lessening in joblessness rate from 3.1% in 2005 to 2.2% in 2008 as appeared in Appendix Table 2.1 additionally flags that the Singapore economy is recouping from financial lull. 1.2 Critical Variables influencing Singapore economy We have recognized a few basic factors that have noteworthy effect on the Singapore economy. They are in particular, the financial approach, monetary arrangement, and outside exchanges. 1.2.1 Monetary Policy One of the key activity of MAS to facilitate the economy is receiving money related arrangement works through controlling the conversion standard to impact the economy to accomplish low swelling and reasonable development, mulling over the way that the idea of Singapores economy is firmly connected in light of the economys dependence on trades and the city-state imports for all intents and purposes the entirety of its needs which will be shrouded in segment 1.2.5 Singapore Export. This brought about MAS depending on the money instead of its loan cost as its strategy apparatus. Right now, MAS has deserted its solid money system wherein it has actualized since April 2004 and has kept up its free fiscal approach zero percent thankfulness for the Sing dollar regardless of a humble recuperation from downturn since 2002 (CNA, 2009a). The keeping up of its casual fiscal arrangement of zero percent valuation for the S$SNEER strategy band came to fruition on October 10, 2009 (Bloomberg, 2009). This new strategy is a finished U-turn of MAS position when MAS required a faster swapping scale gratefulness to sodden swelling a half year prior. Reinforcing the Sing dollar, which has been embraced by MAS since April 2004, is a transition to tame the expanding swelling as Singapores yearly expansion rate has climbed to 7.5% in another 26-year record high (CNA, 2009b). Be that as it may, expansion for the up and coming year is relied upon to fall with the expansion in product costs. In spite of the fact that MAS Monetary Policy Statement doesn't express the purpose behind the new approach with the exception of that the economy is disintegrating and expansion is on the ascent quickly, we break down that the new arrangement will help Singapore exporters over the long haul, and this will be secured under segment 1.2.5 Singapore Export. This will energize a solid development recuperation in the up and coming year and we predict that the Singapore economy will be good for venture in spite of the desolate world economy starting from US downturn. This is because of the way that Singapore doesn't depend just on US however other exchanging accomplices from different countries. 1.2.2 Fiscal Policy On the financial front, the legislature has been receptive to the developing difficulties standing up to the Singapore economy and has implemented it full power. Along these lines, with the beginning of the worldwide monetary emergency and credit crunch, the administration reported a $2.3 billion bundle towards the finish of 2008 to release credit lines and help neighborhood organizations access advances (MAS, 2009). Taking into account the quickly weakening monetary condition, a $20.5 billion (8.2% of GDP) versatility bundle was conveyed to spare employments, to address auxiliary difficulties, help practical organizations remain above water and upgrade the economys long haul capacities. For example, the corporate annual duty rate will be decreased from 18% to 17%, beginning from YA2010, to help seriousness and pull in venture to spike work creation. Furthermore, the administration is likewise squeezing ahead with long haul interests in framework, instruction and social insurance to make Singapore a world-class city. In this manner with these approaches actualized, development rate for Singapore economy is relied upon to rise further in 2010 (IRAS, 2009). 1.2.3 Inflation Swelling happens when request surpasses flexibly, making costs of merchandise and ventures rise. Throughout the years, the Singapores swelling rate has been on an ascent from 0.5% in 2005 to 6.5% in 2008 which is in accordance with the purchaser value file (CPI1) which likewise brought from 100.4 up in 2005 to 110.3 in 2008 as appeared in Appendix Table 1.4 (Government of Singapore, 2009). The ascent in expansion is basically determined by higher food and transport costs in Singapore. This prompts more slow development of the cash gracefully in the economy just as higher financing cost are charged for obtaining cash. Money related Authority of Singapore (MAS) has as of late reported that its expansion estimate for 2010 to be somewhere in the range of 2.5 and 3.5 percent as a surge of outside speculation raises resource bubble stresses (JakartaGlobe, 2009). A fall in swelling implies that the general value level of products will diminish and that shopper buying force will raise, reena cting buyer spending just as the economy. 1.2.4 External Factors The standpoint of Singapores economy is firmly connected to worldwide conditions which is the universal exchange execution. At the end of the day, positive worldwide financial advancements would propose a solid economy in Singapore. Singapores customer value file (CPI1) is driven by outside elements, for example, oil and food item costs which is controlled by the development of the world markets. Developing business sector economies, particularly in Asia, keep on recuperating firmly. For example, Indonesia, Singapores fourth biggest exchanging accomplice, with reciprocal exchange esteemed at S$75.1 billion saw an ascent of 13 percent from 2007 (Borhan. H., 2009). Moreover, private-division financial specialists as of now anticipate that the US economy should extend by 2.7% in 2010, from an anticipated - 2.4% this year, adding further to the splendid standpoint of the fare markets. 1.3 Forecast for Singapore Economy We expect that the development in the first and second quarters in 2010 is probably going to be directed, taking in the way that exportation is relied upon to stay discouraged. In any case, in the second from last quarter onwards, we break down that the economy will move towards positive because of the stimulative strategies actualized by the administrations of its exchanging accomplices. The Singapore economy will hence ride on this influx of financial recuperation and movement. Notwithstanding this is the way that MAS will keep on being watchful over the advancement of the economy and has actualized a progression of approaches. With the proceeded with execution of the S$SNEER strategy, it will additionally fortify Singapores send out business sectors, empowering an expansion in its fare rates because of less expensive products from Singapore. Moreover, the strength bundle which the administration conveyed will keep on procuring beneficial outcomes in the economy as more organizations can tide through this intense period, sparing occupations and expanding work rate all the while. 2. INDUSTRY ANALYSIS 2.1 Overview of Singapore Info Communication Industry We have chosen data correspondence industry as the business reasonable for speculation. Throughout the years, the infocomm business has extraordinarily improved Singapores seriousness by raising efficiency and changing business forms. 2.1.1 Defensive Industry We have indentified infocomm industry as a guarded industry. Media transmission and internet providers are a vital piece of business activity will at present be required even in the midst of downturn. The information correspondence industry plays a significant and fundamental job that underpins the Singapore economy to work as a significant correspondence center point. In that capacity, our chose industry will interest speculators as cautious ventures as the estimations of these stocks are commonly kept up during monetary downturn. 2.1.2 Market Structures Oligopoly The Singapore infocomm industry was changed in April 2000 by IDA to advance rivalry among existing players and make open doors for new market participants. Following that, enormous organizations like StarHub and M1 were granted licenses to set up media communications tasks in Singapore (IDA, 2000). This prompts a progress of the market structure from restraining infrastructure recently overwhelmed by SingTel to oligopoly. Singapores Info-correspondence industry is overwhelmed by three significant organizations in particular, SingTel, MobileOne (M1) and StarHub. As of now, SingTel holds the main situation with a 46.4% piece of the overall industry. StarHub came in second with 27.9% piece of the overall industry while MobileOne stands third with 25.7% piece of the pie starting at 2008 (IR Market Research Corp, 2009). Since an enormous level of the market is taken up by these organizations, they will in general help out one another by maintaining their costs serious to exploit the benefits in the business. 2.1.3 Past Sales and Earnings Performance Singapores information correspondence industry is one of the key supporters of the Singapore economy. From Appendix Chart 2.2, we derive that the general infocomm industry encountered a phase of consistent development during the time of 2004-2008. The income of the business has been continually expanding from $34.77 billion of every 2004 to $58.10 billion of every 2008. This speaks to a general development of 40.2 percent (IDA, 2008a). In view of the pattern given in Appendix Chart 2.2, we construe that the infocomm segment has past the fast increasing speed development and as of now in the phase between

Saturday, August 22, 2020

Offer a Close Comparative Reading Essay

Samuel Taylor Coleridge was conceived in 1772, in Ottery St Mary in Devonshire. During the Romantic period during a period of upheaval from 1770-1830. Right now Britain’s economy was encountering the modern upset, therefore making radical class divisions and an amazingly enormous size of disappointment between the lower classes and the affluent classes. What's more The Enlightenment time drove the sensational change in the manner by which the Western World saw Science, Politics, and Philosophy. Especially English researchers John Locke and Issac Newton shone light upon keeps an eye on previous numbness with respect to material science, science, nature and individuals. ‘Locke’s ‘An Essay Concerning Human Understanding’ (1690) was tremendously persuasive, because of his philosophical reasoning and his mechanical hypotheses on nature. The significant perspectives in the eighteenth Century shaped the world wherein we live in today. The sentimental writing of this age was a ‘product of the monetary and social time frame in which they lived in. It is said that ‘the deconstructive perusing of Romanticism stressed its incongruities, its reluctance and the complexities of the manners by which it united way of thinking, writing and history. Most of sentimental writers, particularly William Wordsworth and Samuel Taylor Coleridge were malcontented in this time of science and reason because of the mechanical method of thinking,and the ’emphasis on precision, reason and improvement that it showed. Coleridge and Wordsworth thought this constrained the limit of the brain. They accepted that there was a ‘deeper reality inside the material world and that our otherworldly nature can be acknowledged using our minds. Anna Barbauld (1743-1825) was another very compelling English artist of the eighteenth Century, conceived in Kibworth, Leicestershire. What's more, alongside preferences of William Wordsworth, Samuel Taylor Coleridge and Robert Southey they characterized Romantic verse. Barbauld was a well known female author, and during this time of male controlled society this was very unprecedented, as ladies in this period were placed in a sex job in the public arena fitted into the job of the household world and not in the open world. She had an enchanted existence, and learned at Warrington Academy, and educated Greek and latin, ‘Barbauld was raised as and stayed a supporter of the liberal ramifications of Enlightenment thought. Judiciousness, empathy, and law based human rights were the backbones of her political positions.  She was known for her commitment to sentimental time, and during her lifetime was appreciated for her ability by the youthful Samuel T. Coleridge. Barbauld had a concise association with Coleridge. ‘Anna Barbauld had a progressively mind boggling relationship with the youthful sentimental artists, not least since she lived well into the nineteenth century and she was progressively treated as a leftover from another age.  Her sonnet, ‘To Mr Coleridge’ in 1797 is concerning her gathering with him when he was 25 years old, he had strolled to Bristol to meet with her and to wished to show her a scope of his verse at that point. The sonnet reflects Barbauld’s introductory impression of Coleridge, and her underlying judgment of his character, ‘counseling him to give more consideration to his obligation and movement, and to keep an eye out for sluggishness.  It is certain that the sonnet, ‘To Mr Coleridge’ has a review, and negative manner of speaking as she gives her negligence for Coleridge’s humanistic view on the world and his unimportant composing style, as she starts the 43-lined sonnet considering his work, and a conspicuous normal setting, ‘Midway the slope of science’. I think Barbauld intentionally picked ‘midway’ to speak to a spot in his profession. The sonnet utilizes a metaphorical interpretation of Coleridge’s visit as Barbauld depicts the forest in line 3, †A Grove stretches out, in tangled labyrinths wrought,’ a forest is a reference to a little woodland or nursery, here Barbauld is utilizing the forest allegorically as an image for Coleridge’s creative mind. As ‘Romantic artists accept that the creative mind is fundamental’. she is attempting to recommend that inside this ‘grove’ makes the view of the outside world distorted, as she shows that it seems to be, ‘fill’d with odd charm:- questionable shapes’. She makes a variety of characteristic imaginings along Coleridge’s venture, Barbaulds, ‘To Mr Coleridge’ has a fantasy like quality. The symbolism utilized in the initial fourteen lines, for example, ‘fill’d with unusual enchantment’, ‘gloom and spiritualist visions’ and ‘filmy-net’ speak to how Coleridge supplanted the precise perspective that the illumination achieved by John Locke and Issac Newton, by trusting in something different which we can't see or control. Coleridge accepted that, ‘A sonnet is that types of sythesis, which is against works of science In lines 10-13 Barbauld is scrutinizing how Coleridge sees an item, ‘obvious to locate and touch’, Coleridge was consistently ‘concerned with the issue of how the idyllic brain acts to alter or change the materials of sense without abusing reality to nature.  An legitimate tone can be recognized by Barbauld in the lines, ‘Filt thro’ diminish dales, and bait the excited foot | Of energetic fervency to endless chase’. She features his age with the word ‘youthful'(line 6), recommending that he unpracticed is still yet to learn numerous things about the world and be practical in his perspectives. Line 19 uses the word ‘Indolence’ which was a watchword in the hour of the illumination, which means, lethargic and inactive. Like ‘most youngsters of the time with a grain of vision he was blended by the progressive enthusiasms of the mid 1790s'[12] She permits draws on Coleridge’s ‘vacant mind’ (line 22) Coleridge accepted that the psyche was ‘the source and the trial of art'[13]. The reoccurring topic of ‘youth’ likewise gives the sonnet a belittling component. ‘Barbauld was an abstract appointed authority from the more seasoned age, and, through their legislative issues agreed for a period, her integrity was most likely not exceptionally ameliorating to Coleridge'[14] making the age hole between the two evident in the sonnet. The all-inclusive illustration of the slope of science can be viewed as an allegorical excursion, ‘Here each psyche | Of better form, intense and sensitive | In its high advancement to endless truth’, the speaker in the sonnet is portraying the occasions of an excursion through the english open country, yet a portion of the things referenced aren’t present, here we can see that Barbauld implying crafted by Coleridge, yet thoughtfully proposing that he has far to go before arriving at his maximum capacity. Barbauld accepts that Coleridge is dismissing social and political setting. Lines 32-34, ‘ Youth belov’d | Of Science †of the Muse belov’d not here, | Not in the labyrinth of allegorical legend. ‘ Barbauld suggests that Coleridge doesn't have a hang on the real world. The ‘spleen-took care of fog'(line 40) that is being alluded to is an illustration for Coleridge’s lost sight along his way, and she offers to his Unitarian nature by completion the sonnet with ‘Now Heaven direct thee with a Parent’s love’ (Line 43). ‘This Lime-Tree Bower My Prison[15] by Samuel Taylor Coleridge was additionally written in 1797 and is a portrayal of an excursion, correspondingly to Barbauld’s, ‘To Mr Coleridge’. Coleridge composed the sonnet after he couldn't join his companions on a stroll all through the open country, because of a physical issue, his significant other had unintentionally burnt his foot with bubbling milk, bringing about Coleridge left under the Lime-Tree considering all the sights that his companions would experience. In Coleridge’s sonnet he utilizes the speakers line of reasoning as the account for the sonnet as he breaks his own physical limitation and intellectually takes the excursion. The sonnet utilizes a conversational tone, starting the sonnet with, ‘Well. ‘ likewise, because of it being clear stanza this permits Coleridge to not need to keep a reliable rhyme plot or a meter for the sonnet, and the conversational component includes closeness for the peruser as he portrays at first what his companions will experience on their walk, ‘the artist both watches and contemplates so anyone can hear as he tends to a quiet audience. ‘[16]. A significant number of Coleridge’s conversational sonnets were straightforward and had no idyllic structure. In the primary verse of the sonnet there is hatred and disengagement spoke to in Coleridge’s irritable state of mind as the speaker says, ‘I have lost | Beauties and feelings’ (line 2-3), tending to himself as the ‘I’ in the sonnet we have a feeling of an egotistical Coleridge, he is sat underneath a lime-tree as he pity’s himself over his physical issue that shields him from taking a stroll with companions. The utilization of monosyllabic words in the principal refrain backs up Coleridge’s mentality to his ‘prison’ toward the beginning. His mentality before long starts to change once he starts to record his succession of considerations, ‘That at the same time (a most phenomenal sight!) and he at that point changes from self indulging to envisioning, he interfaces with his environmental factors and appreciates having the option to encounter nature through his companions venture. It is as though Coleridge has a revelation as he has a snapshot of acknowledgment through his creative mind. Toward the start of refrain two there is a huge progress in Coleridge’s discernment, beginning with ‘Now’ (line 21) we can see that the speaker has considerations have altered course and has become a state of inversion, as he starts to re-make the excursion through Charles Lamb, who he addresses in the sonnet, a nearby frie

Monday, July 27, 2020

Advancements in Healthcare and Medicine

Advancements in Healthcare and Medicine Throughout human history, each passing century has brought revolutionary changes to healthcare and medicine. Between 1914 and 2014, we have extended the average human life expectancy rate by approximately 25 years, due to discoveries like penicillin (in 1922), inventions like the cardiac pacemaker (in 1952), and achievements like the eradication of smallpox (1980). In this time period, we have learned to repair hearts, mapped DNA, and even performed a partial brain transplant, accomplishments, once inconceivable, but now commonplace. Conforming to the trajectory of history, new advances in science, engineering, and computer technology will revolutionize healthcare and medicine over the course of the next century. The roots of this change are already visible today. © Shutterstock.com | Andrey_PopovIn this article, we will explore: 1) recent trends and advancements in healthcare medicine, 2) gene therapies using stem cells, 3) robotics in medicine, 4) electronic medical records, 5) biotechnology, 6) telemedicine, and 7) other promising trends in healthcare medicine.  RECENT TRENDS AND ADVANCEMENTS IN HEALTHCARE MEDICINEPerhaps nothing in modern history has had such an impact on the fields of healthcare and medicine as the advent of the Digital Age. The adoption of computer technologies in healthcare and medicine has led to new practices, treatments, and methods that have saved hundreds of millions if not billions of lives over the past quarter-century. Once unfathomably complex medical research is possible today with just a few keystrokes. And healthcare delivery, medical record-keeping and doctor-to-doctor collaboration have all been made more efficient and effective.As computer technologies improve, great strides will continue to be made. Some of the biggest computer-driven medical new advancements since the year 2000 have included:The adoption of the computer by medical professionals;The decoding of the human genome;The rise of stem cell research; andThe development and use of the functional MRI (fMRI) to map brain activity.Of course, not all advances have been as significantly driven by new and emerging computer technologies. Others have included:The increasing life expectancy of HIV-positive patients;The reduction of invasive surgery through the adoption of non-invasive surgical techniques;The use of targeted therapies in cancer treatment; andThe discovery that the use of Hormone Replacement Therapy, once commonly used to treat menopause symptoms, is life-threatening.Of course, due to global inequities in healthcare access and delivery, these trends and advances are of far more relevance to those in developed nations. A report, “Global Health 2035: A World Converging within a Generation” from a global commissi on co-chaired by former U.S. Treasury Secretary, Larry Summers, noted that these inequities could be eliminated within a generation given our current trajectory of medical advancement, and increases in global investment in medical RD. Given the tremendously beneficial potential of probable medical advancements, such as gene therapies, hopefully advancements in healthcare delivery keep pace.  GENE THERAPY USING STEM CELLSOverview © Wikimedia commons | National Institutes of HealthOne of the most promising advances is the use of stem cells in gene therapy. Gene therapy involves the insertion of healthy genes in a person’s cells to replace unhealthy ones, by means of a virus. The National Institutes of Health (NIH) defines stem cells as having two important distinguishing characteristics:  First, they are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity. Second, under certain physiologic or experimental conditions, they can be induced to become tissue- or organ-specific cells with special functions.Research has involved the two main types of stem cells: embryonic stem cells and adult stem cells. Within the past ten years, researchers discovered a way to program some adult cells to assume a stem cell-like state. These are known as induced pluripotent stem cells.  Research trendsMuch research regarding stem cells has been driven by ethical con cerns about the use of embryonic stem cells: namely, the ramifications of conducting experiments on cells that could under the right conditions develop into human beings. In the United States, Presidents Bush and Obama have enacted and maintained restrictions on federal funding of embryonic stem cell research, but have not outlawed it. However, six states have. In Europe, outright bans of embryonic research exist in Lithuania, Austria, and Germany; restrictions exist in all other countries. By contrast, Asian countries have the loosest restrictions on stem cell research in the modern world.Beyond the legal and ethical considerations, key stem cell research trends, according to a research trends analysis of academic publications involving stem cells over the past six years, have been: 1) regenerative medicine; 2) drug development; 3) applications of induced pluripotent stem cells; and 4) policy analyses of stem cell research.  Current applicationsCurrently gene therapy treatments usi ng stem cells, are relative rare because the treatments are expensive and complex. There are also still many unknowns and many risks, including a cancer risk â€" the inserted genes can activate nearby cancer-inducing genes. Because of the unknowns, there are also ethical concerns regarding human trials.    Future possibilitiesDespite the challenges, many researchers are optimistic about the potential of this treatment method. It has the potential to provide an effective cure for diseases that are currently incurable. Gene therapy using stem cells could be used to repair damaged organs and reduce the number of people who need transplanted organs. This method could also be used to repair burn damage. Finally, this innovation could be used to safely test pharmaceutical drugs before they are introduced to humans.  Gene Therapy The time is now: Nick Leschly at TEDxBoston ROBOTICS IN MEDICINE © Flickr | Army MedicineOverview Robotics technologies have come a long way from George Devol’s industrial robotic arm of 1961. The sensing, thinking, and adapting technologies, which are the hallmark of robotics have been refined for use in healthcare and medicine. Today, robots like Aethon TUG and the Vasteras Giraffe deliver medicine and/or medical equipment in hospitals, unmanned robotic surgeries are available to patients, and exoskeletons that enable paraplegics to walk are on the market. These are just a few of the advancements in robotics technology that are transforming the fields of medicine and healthcare.  Research trendsCurrent research in medical robotics primarily includes the use of robots in rehabilitation therapy, disabled and elderly patient assistance, drug delivery, minimally invasive surgery, image-guided surgery, patient monitoring, and biological systems modelling for diagnoses, among other areas.  Current applicationsService robots â€" robots designed to a ssist people perform a specific task, usually one that is tedious or dangerous, are commonly employed in hospitals to assist in patient care, and to transport medical equipment. Other types of robots, such as the Da Vinci, assist doctors in the performance of surgeries. Smaller robots, like the ViRob Miniature Medical Robot, are introduced into the patient’s body and deliver drugs directly to sites of infection. Still other robots, like the RIVA, are designed to dispense intravenous solutions and/or pharmaceuticals to patients.  Future possibilitiesSome medical practitioners and futurists predict that robots, in humanoid form, will play an increasing role in patient care. Others predict the advent of increasingly smarter robotic surgical tools. These may be external or internal, as we grow better at developing capable miniature robots. Further, as government adoption of service robots becomes more widespread, robots may be deployed to provide medical assistance in disaster areas o r battlefields.Advances in robot technologies will be critical in refining exoskeleton and prosthetic technologies. And artificial replacement limbs could give rise to humans with augmented capabilities.  Robot Surgeons are the Future of Medicine ELECTRONIC MEDICAL RECORDSOverview The continued adoption, refinement, and usage of electronic medical records (EMRs) by hospitals has been a goal of the medical community for many years. Before the advent of EMRs, disparate recordkeeping methods and sharing protocols led to errors in the administration and delivery of healthcare. A single badly written document could lead a doctor to prescribe a type of medication to which a patient might be allergic. Further, even inside a single hospital, there might be disparate systems for pharmacy orders, records, and other parts of a patient’s record. Standardizing, consolidation, and digitization of records cannot only improve patient care. It can also provide hospitals and data experts a treasure trove of data to be mined for medical research.  Research trendsWhile real privacy and implementation issues currently exist, we have begun to use the Internet for many fundamental transactions, such as banking. Websites, such as WebMD, have put medical information at the fingertips of many patients, acclimating them to online medical information and making them active participants in their own care. It is not unexpected that we would be open to â€" and indeed even expect â€" our medical records to be integrated into our online lives. The ubiquity of mobile health or mHealth is also fueling patient openness to EMR, which in turn is fueling increased medical investment in such systems. Also fueling this increased investment: new wireless technologies, like remote monitoring and telemedicine, that benefit from data and input.  Current applicationsToday, approximately 80% of physicians use an EMR of some type. 8 out of 10 of these reported improved patient care due to their use of onl ine medical records.  Future possibilitiesMany doctors, nurses, and patients dream of the days when new patient forms are auto-populated, records are seamlessly shared between doctors and referrals, and other features that will greatly increase the personalization of care. Further, EMR will fuel the adoption of other projected trends such as self-service kiosks for hospital registration, full home diagnostic systems, GPS tracking of patients with dementia, semantic databases, and use of large data pools by medical researchers and public health experts to predict outbreaks.  EMR/EHR Done Right BIOTECHNOLOGY © Flickr | Umberto SalvagninOverview Biotechnology, which is the technologies associated with the manipulation of living tissue and organisms, is another field in which the breakthroughs of the near future promise to transform our world. Biotechnology has been used for centuries, notably in agriculture and cross-breeding of animals, but only recently, with our greater understanding of biology on the cellular level, have we begun to explore the full potential of the field.  Research trendsMedical biotechnology research usually revolves around solving diseases. Creative approaches to diseases may come not from a trained physician but the educated layman, as many of the resources once exclusive to high-end laboratories are available to the public. The creation of artificial organs is another aspect of biotechnology that has garnered much attention both inside and outside of the medical community. A third area of biotechnology that holds considerable promise is nano-biotechnology, which uses biological tissues to create nano-devices and nano-particles that can then be used to address biological issues.  Current applicationsGene therapy using stem cells is a good example of biotechnology, as is bioprinting (see below). Cloning, genomic analysis, antibiotics, and DNA profiling (a keystone of forensic analysis), are other notable examples. But they likely only scratch the surface of the possible.  Future possibilitiesIn time, biotechnology may allow us heretofore unparalleled medical advantages. Scientists are currently using the field’s methods to explore:Decay-fighting microbes;Biologically-based pacemakers;Spit tests to diagnose cancer;Asthma warning sensors;Stents that dissolve in the bloodstream;Nerve regenerators;“Smart” (autonomous) wheelchairs;Augmentation via prosthetics; andComplete models of biological systems.These are just a few of the possibilities. By 2114, biotechnology may have eliminated the very need for many of these innovations.  Bringing b iotechnology into the home: Cathal Garvey at TEDxDublin TELEMEDICINE  Overview To make sure that the most people benefit from these innovations, the medical community must also look at how they can more effectively deliver healthcare. Enter telemedicine â€" which involves the remote delivery of healthcare and medical services. In developed nations, this applies to rural areas in which residents lack easy access to medical or hospital facilities. In developing nations where access to healthcare is generally more limited, this has far broader implications and potential benefits.  Research trendsExperts predict anywhere from an 18.5% to a 56% annual growth rate in the tele-health market worldwide through 2018. This massive growth is supplemented by advances in and refinements of remote monitoring technologies, EMR, and service robots built for domestic care, and research in and development of more robust home diagnostics and remote touch. Telehealth is also driven by related computing trends, such as enterprise mobility management, cloud computing, and social networking.    Current applicationsApplications of telemedicine can be seen in the provision of medical advice by healthcare providers to patients through social networking, mobile devices, and videoconferencing. Service robots are now used to provide homecare and remote monitoring to patients in need. Remote monitoring of discharged patients is another example of telemedicine currently in practice.  Future possibilitiesThe potential benefits of telemedicine are significant. Use of this healthcare delivery method can reduce the overall costs of healthcare making it less expensive for, and more accessible to, the consumer, as well as leaving more money for research. By completing diagnoses remotely, telemedicine can filter out those not needing hospital visits from those who do, making healthcare delivery more efficient. It can heighten patient awareness and active management of their own health. Telemedicin e can also increase healthcare access in areas traditionally lacking it.Telemedicine enthusiasts envision a day wherein home diagnostic, medical robots, and medical equipment, along with wireless connectivity and EMRs integrate seamlessly to allow all but the most serious of patient ills to be treated remotely.  Jennifers Story How Telemedicine works OTHER PROMISING TRENDSThese are not the only trends that promise to revolutionize our world. Bioprinting the use of additive manufacturing processes and 3-D printer technology to create living tissue and organs, may make organ donation a thing of the past. In fact, bioprinting could be used to synthesize drugs (prescribed remotely of course), making pharmacies a thing of the past as well. Advancements in wearable tech have significant implications for remote healthcare devices. And innovations in virtual reality will us to better train medical students, diagnose medical conditions, test medical treatments, and improve overall patient care.  ChallengesAny of the aforementioned breakthroughs may be stymied by the economic and regulatory environment of a researchers or research teams home country. The politics of, and finances available to their sponsoring organization, will play a role. Testing and adoption by the medical community and consumers, as well as standardization of products (i.e. common record-keeping protocols for disparate EHR systems), will affect how quickly the benefits of new medical technologies reach those in need.  Future possibilitiesHowever, the collaborative tools, the computing power, and most importantly, the curiosity to solve some of our most challenging medical mysteries exist. By 2114, we may have used biotechnology to retard the aging process, gene therapies to eradicate all current forms of disease, and domestic robots to replace doctors and hospitals. One thing is for sure; the future of medicine a century from now will look very different than that of the present day. Image credit:  Wikimedia commons | National Institutes of Health under public domain, Flickr | Army Medicine and Flickr | Umberto Salvagnin underAttribution 2.0 Generic.

Friday, May 22, 2020

Building A Target Conformant And Flexible Enterprise...

Introduction: In order to build a target-conformant and flexible Enterprise Architecture, and to put it in a perspective, it is very important to analyse and visualize various academic and industrial frameworks and comprehend and define its concepts. Various definitions describe different architectural processes, systems, technologies, components and their relationships (Taleb et al, 2012a).The following section discusses three industrial and three academic frameworks which provide different viewpoints of Enterprise Architecture. Analysis: Figure 1 Viewpoints on EA Conclusion: An analysis of various industrial and academic viewpoints of Enterprise Architecture provided an insight on the inferences that can be derived from Enterprise†¦show more content†¦The importance of culture and organizational structure and the integration between them is discussed in-depth as well, in order to state the factors that need to be focused on for design of an enterprise. Bernard has further elaborated on various organization models and scrutinized them to justify the distinction between organization and enterprise. Associated risks and process of estimating the cost and benefits are eventually explored, covering several important aspects of EA. Evaluation Enterprise Architecture is defined as ‘a coherent whole of principles, methods, and models that are used in the design and realization of an enterprise’s organizational structure, business processes, information systems, and infrastructure’ (Lankhorst et al, 2012). Over time, EA has become an integral part of organization’s strategy rather than being a mere guideline, (Vaidyanathan, 2005) motivating organizations to design business-aligned enterprise systems. The author’s representation of EA as a strategy, business and technology-driven process and its meta-disciplinary role thus seems accurately described. Decisions taken are often incomplete without an adequate decision supporting frameworks (Narman, 2012). Several organizations have adopted EA frameworks in order to maintain links with other systems and ultimately create integrated systems, similar to building blocks that fit together (Shah and Kourdi, 2007). The author’s knowledge

Friday, May 8, 2020

Agriculture Evolution or Devolution Essay - 1259 Words

Agriculture: Evolution or Devolution? Considering that the alarming excess and continuing growth of the current world population (of humans) is directly tied to food production and availability, the question of how and why we even developed the technology of agriculture in the first place is becoming more and more relevant to human survival as we collectively continue to destroy the environment in which we live due in part to these very agricultural techniques and strategies that we are continuing to employ today. Current estimations show that at around the same time that agriculture was beginning to develop and thrive, the population of our ancestors started to double at a rate that was far higher than what it had been previously†¦show more content†¦Paul R. Ehrlich finds much fault with the way humans are in his eyes well on the path to self-destruction through population explosions and irresponsible use of technologies. But when he goes on to examine the non-technological aspects of the human self-destructive patterns, he explores possibilities of humans having a natural tendency towards violence (Ehrlich, 210). Even though he does not agree with the view that humans are genetically prone to do acts of violence, and acknowledges that there are different kinds of and reasons for violence, his assertion that the roots of this destructiveness lie in culture present another problem (Ehrlcih, 226). The problem is that this puts all the human beings who are born to and participate in this culture, whether willingly or not, into one category of humans who are essentially deficient, if not because of their genes, then because of their culture, and this leaves no room for the collection of individuals who feel uncomfortable within such a culture. For example, though I do not want to endorse a society that puts money and egocentric ideology above and beyond all else, in a way I am doing just that by typing these words on my power-consuming computer (which is already an outdated one even though pu rchased only a year and a half ago), or by buying my food, which is frequently packaged in plastics or metalsShow MoreRelatedEvolution of Populism and La Moral from Modernization Populism refers to the political philosophy1100 Words   |  5 PagesEvolution of Populism and La Moral from Modernization Populism refers to the political philosophy that pits the downtrodden masses against the apathetic ruling elite. La Moral refers to the conformity to the code of conduct set by employers. Modernization is the transformation from a traditional, rural society that primarily relies on agriculture to an urban, industrialized society. The emergence and flourishing of modern society has been inextricably linked with the development of industries, infrastructureRead MoreEnvironmental Issue in the Philippines2021 Words   |  9 Pagesin coastal villages. Mangroves have particularly suffered from coastal development, notably at the hands of the aquaculture industry. In the Philippines, aquaculture has reduced mangrove stands to only 36% of 1900 levels. The evolution of the present regulations governing fisheries can be traced as far back as the Spanish Law on Waters in 1866, which recognized the right of the public to fish from the shore and granted rights to Spanish registered seafarers and merchant sailorsRead MoreDevolution of Local Government in the Philippines5838 Words   |  24 Pagesstrengthen people’s participation in the affairs of the government†[3]. Different forms of decentralization can be distinguished primarily in terms of the extent of authority transferred and the amount of autonomy. Decentralization may take the form of devolution and deconcentration. Deconcentration involves the â€Å"redistribution of administrative responsibilities only within the central government†[4]. It is not a transfer of power from the central government but merely to â€Å"delegate such powers and responsibilitiesRead MoreStudy Plan Pakistan Studies2636 Words   |  11 PagesPrepared by: Altaf Ahmed Sheikh - CSS - 2011 Altafsheikh1988@gmail.com Composed by: Redmax! PAKISTAN AFFAIRS STUDY PLAN Study Area – I: Evolution of Muslim Society in the Sub-Continent 2007 – Critically evaluate the contribution made by missionaries in the growth of Muslim society in the Sub-continent of Indo-Pak. 2006 – Describe the most notable feature of Muslims in India in the light of their monotheistic religion and egalitarian social structure. 2005 – Summarize the political scene of the subRead MoreAgricultural Revolution Essay2448 Words   |  10 Pagescauses us to become dependent on others for survival. Humans existence is attributed only to the million years of evolution our food source underwent to sustain our survival. Changing the primary nature of our food source, whether it is plant or animal, directs mankind in a dangerous future if our food dependency is permanently hampered. Welcome to the age of an agricultural devolution indeed. The year 1980 marks the beginning point bioengineering becomes an emerging technology, radicallyRead MoreThe 1976 Local Government Reform and Physical Planning Development in Nigeria2611 Words   |  11 Pagesas the staff and institutional and financial powers to initiate and direct the provision of services and to determine and implement projects so as to complement the activities of state and federal governments in their areas and to ensure through devolution of functions to these councils and through the active participation of the people and their traditional institutions that local initiative and response to local needs are maximized. The idea being one manufactured by a military regime, hasRead MoreIndia and China Comparative Economic Analysis5875 Words   |  24 Pagesconsidered essential that the public sector occupy the economys commanding heights. However, that did not prevent entrepreneurship from flourishing where the long arm of the state could not reach. The factors that govern India and China’s economic evolution, advancement and their future sustainability can be examined through the following key issues and questions; 1. Why India and China are inevitably compared? 2. The past directions of growth that the two economies have followed and the factorsRead MoreUK - Analysis Report31935 Words   |  128 Pageslocation PESTLE analysis Summary Political analysis Economic analysis Social analysis Technology analysis Legal analysis Environmental analysis Political landscape Summary Evolution Structure and policies Performance Outlook Economic landscape Summary Evolution Structure and policies Performance Outlook Social landscape Summary Evolution Structure and policies Performance 1 1 1 9 9 10 11 11 12 15 19 22 25 28 30 30 30 33 38 39 40 40 40 41 44 54 56 56 56 57 61 United Kingdom: Country Analysis Report –Read More Monogamy and Marriage: The Battle Between Biology and the Buck4707 Words   |  19 Pagessome reference will be made in the conclusion. The history of human pair-bonding and marriage systems can be divided into three major periods of time: (a) from early primordial time to the time of hunter-gatherers; (b) the time of agriculture and pastoral herding; and (c) the time of industrial-commercial societies. Through these three main phases of history, economic factors have played the most important role in shaping the human mating system. The watershed dividing the firstRead MorePlachimada Case Study13995 Words   |  56 Pagesis a small hamlet in Palakkad district. It is also home to several scheduled caste and scheduled tribe populations. The villagers are predominantly landless, illiterate, agricultural labourers. Almost 80 per cent of the population depends upon agriculture for their livelihood. Hence, it is most likely that, the location of an industrial plant, which consumes water heavily, in a socially and economically backward, in a region that is agricultural but drought prone would result in serious adverse implications

Wednesday, May 6, 2020

Addressing Gary’s Aggressive Behavior in School Free Essays

From The Four Mistaken Goals of Children’s Misbehavior – Diagnosis and Remediation (cited from Dreikurs and Soltz, 1987), these goals are seeking undue attention, power, revenge, and inadequacy (PSYCHOTHERAPY INSTITUTE). Gray’s case falls in the goal seeking undue power. In this type of mistaken goal, there are still 2 types: the active power and the passive power. We will write a custom essay sample on Addressing Gary’s Aggressive Behavior in School or any similar topic only for you Order Now The active power is the one which the child sees himself and acts like a boss to other people around him. On the other hand, passive ones would refer to those that do not allow themselves to under the authority of other people. Basically, being a new student in Ms. Adams fifth grade class, Gary’s primary response is to be defensive of his own self. People like Gary creates the I’m-in-charge atmosphere and, feeling that they are the boss, they refuse to cooperate with other people. According to the Psychotherapy Institute the effective way to deal with this kind of behavior is for Ms. Adams to not to tolerate Gary’s behavior. Primarily, she should listen first to Gary. There should have a communication between them as to why the child misbehaves himself and its effects to other people. Choices must be also available for Gary. When he misbehaves, he should be redirected to a similar yet pleasing manner (University of New Hampshire Cooperative Extension, 2002). Bargains should be made such that the child is not acknowledged of his misbehavior instead made to do something more agreeable. In here, some privileges too can be suspended due to his misdemeanor (Keep Kids Healthy, 1999). Schools have different strategies in dealing with student misdemeanors. To deal with them is one of the major aspects in classroom management in which educators, administrators and parents are to provide a safe, compassionate and well motivated environment for everyone especially the children (Blomberg, 2004). Misbehavior in School References Blomberg, N. (2004). Effective Discipline for Misbehavior: In School vs. Out of School Suspension. Villanova University: Department of Education and Human Services. Dreikurs, R. and Soltz, V. (1987). Children: the Challenge. OK, USA: Plume. How to cite Addressing Gary’s Aggressive Behavior in School, Essay examples

Tuesday, April 28, 2020

Royal Bodies free essay sample

Evidence from history proves that the Ancient Greek civilization was obsessed with Idols. From their superhuman strength to their unparallel beauty, mere mortals have gravitated towards images greater than they are. This holds as much truth today as it did four thousand years ago. In todays culture, instead of praying to false Idols, we are obsessed with the idea of celebrity due to the impact that the media holds. The media, to be specific is obsessed with celebrity and vice versa; due to the power that each holds. When a magazine puts someone famous on its cover, people are more nticed to buy it. Hilary Mantel dares to make the rather obvious point that the royal body is public property. She describes the Duchess as becoming a Jointed doll on which certain rags are hung , a shop-window mannequin, with no personality of her own. Mantel states that it is important that the Duchess of Cambridge is young, pretty and now demonstrably fertile. We will write a custom essay sample on Royal Bodies or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page She contrasts Kates all-important reliability to the tragically unstable egos of Marie Antoinette and Diana, Princess of Wales, writing that the Duchess seems to have been selected for her role of princess because she was rreproachable: as painfully thin as anyone could wish, without quirks, without oddities, without the risk of the emergence of character. Living in a technological era, we have access to the tabloids more than ever before. There are television sets, magazine covers, Internet blogs, and movies screaming to be read and watched, and they are plastered with images of these tacky celebrities. Now, in an age where we have more contact with celebrity gossip than we have ever had, we are faced with a question: what are the effects that superstars have on our youth? Celebrities influence fans to be destructively thin, put harmful substances in heir bodies, and many parents are concerned with the overall content these celebrities are putting on television, in movies, and over the Internet. Pop culture idols need to think twice before making a poor decision or practicing awful morals because of their influence on their young fans and other people who may look up to them. Even reality television plays a factor into the medias obsession with celebrity. MTV has a show called l Want a Famous Face which highlights ordinary people who undergo several thousands of dollars worth of plastic surgery to achieve a look of a celebrity that they admire. We as a society are intrigued with lives far greater than our own. We look up to these undependable Idols to motivate us. Their beauty and status gives people something to strive for and imagine being a part of. The media as a whole feeds this obsession and is showing no sign of stopping anytime soon. Their effect is especially evident in their appearance and attitudes. With celebrities creating impossible standards of beauty, more and more young adults are feeling less confident, more angry, and more dissatisfied with their looks (National Institute on Media and the Family). Now, this cannot all be blamed on the media, but with celebrities becoming thinner and thinner, much selt-contldence is lost and images ot television stars or models have been connected to body displeasure (National Institute on Media and the Family). With television shows today including sexual content, violence, and adult language, children are exposed to unsuitable matter for their ages. Since many parents work and are not always at home, kids have access to shows, movies, and the internet blogs that can tell them things that should be left for parents to explain. Stars need to be more aware of their images because some are llowing younger fans content that many parents do not want their child seeing. Celebrities have glamorized smoking in the media and are setting an example for supporters everywhere that it is acceptable to smoke. Pop culture icons need to support a drug free program instead of using harmful substances. In the past, people learned how to live through religion and fear. Now, with fewer and fewer people attending Church, celebrity culture fulfills a certain spiritual value that is otherwise lost. Mantel said Kate had gone from being a Jointed doll on which certain rags are hung to a woman whose only point and purpose was to give birth. She continued to say Kate appeared to have been designed by a committee and built by craftsmen, with a perfect plastic smile and the spindles of her limbs hand-turned and gloss-varnished. What bothers me is that someone can Judge the duchess from the outside with never having experience within the Royal family or even being a celebrity. Hearing these things about the Royal family is like a chapter out of the bible for how to live like a royal. People get so obsessed with hearing trash talk about people who live better lives than themselves. In the medias rush to take snippets ut of context and highlight the piece as royal-bashing the Duchess of Cambridge, they are completely missing the speculative insight of a royals physicality. In the face of both royalty and celebrity, we are all too quick to forego ones humanity. Celebrities need to change the way they act and how they are viewed. Their actions have more of an effect on us then many people believe they have. Thin, addicted celebrities are changing the way many young fans think and act. Celebrities need to change these horrible habits now and realize that they need to be more concerned with themselves and with their portrayal in the media.

Friday, March 20, 2020

Essay About Your Goals

Essay About Your Goals Goals, or goal making, can be applied to so many aspects of life: success, health, productivity, projects, and relationships – the list is endless. People set goals to meet an objective, either on a short- or long-term basis. Some goals, like writing a book and publishing it, may take a number of years to accomplish. What Is a Personal Essay A personal essay is a kind of narrative essay where the author tells about a certain life incident or something that has had a significant impact on him or her. It may also speak of a lesson learned, or simply express a point of view on some issue, which was of vital importance to the author. The personal essay appears to be one of the richest and most vibrant of all literary forms. The personal essay is also one of the most popular forms of creative nonfiction. ESSAY FORMAT If you are looking for personal essay examples here is a great one below. Read and enjoy! â€Å"Setting goals is the first step in turning the invisible into the visible†   Tony Robbins Goals, or goal making, can be applied to so many aspects of life: success, health, productivity, projects, and relationships – the list is endless. People set goals to meet an objective, either on a short- or long-term basis. Some goals, like writing a book and publishing it, may take a number of years to accomplish. While some goals are set for a day, a week, a month – but all goals are different and require different lengths of time to accomplish. They serve to motivate, to remind and to monitor, for people who want to improve themselves, to become successful or try something new. As a college sophomore, at 20 years old, I am in the beginning to see the benefits of setting goals. One of my goals I set in high school was getting into Columbia University in New York City, and I hit that goal. Now I’m there studying business and marketing, where I am still making and hitting my goals. Two I’ve set myself is graduating in two years with a degree and graduating with a grade point average (or GPA) of 3.5. A college degree, especially one from an Ivy League school, will open many doors for my future career – and graduating with a high GPA will almost ensure me of at least tons of interviews once I graduate. However, I also have a goal of getting an internship, to have practical, real-world experience in the field of business and marketing. This I plan to get before I graduate so that I can start applying for jobs the moment I get my degree, or even before I get my degree. (Another goal is finding a job that really challenges me, a job I love and which does not feel like work at all.) Others goal I have to pertain to my personal and family life. Once I have landed a good, fun, high-paying job, I hope to enter the dating scene: to find someone to love and spend my life with. That’s what everyone wants and what many people work hard for. My goal is to meet the right girl who understands me, challenges me and appreciates me for who I am, a person who will complete me and be there for me when times are bad, as well as when they are good. Finding and keeping the right person is all that truly matters in this life – and that is what I want and will get. Also, my goal is to start a wonderful, loving family that will come to take care of me when I’m old, weak or weary. Lastly, another goal I have is having financial success, to be able to live a long, healthy life. It’s something I never saw in parents, as both are working-class people who have struggled with debt and other financial hardships. Even to this day, they sometimes work paycheck-to-paycheck and stress about paying bills, struggling and never going on vacation. I don’t want that life. I want, I need, I deserve, financial freedom – the freedom to live a life free of the fear of going broke, homeless, becoming poor – and a life completely free of the worry of having enough money. No, money and a good career are not everything. Just half. You also need people in your life to love, who love you back, and who provide meaning to life. This cannot happen without setting and hitting goals, then setting more and hitting more. It’s a life-long practice used many successful people all across the board. And it’s something everyone could benefit from at some point in his or her life, in any and all aspects of it. It works, and it’s been proven to help people become a better version of their self. If you need help with personal essay writing feel free to contact our support team or place an order right now and we will gladly help you.

Tuesday, March 3, 2020

U.S. States Ranked by Area

U.S. States Ranked by Area The United States is the worlds third largest country by area, ranked behind Russia and Canada. Within that large are 50 states that vary widely in area. The largest state, Alaska, is more than 400 times larger than Rhode Island, the smallest state.  Including water features, Alaska is 663,267 square miles. In contrast, Rhode Island is a mere 1,545 square miles, and 500 square miles of that is Narragansett Bay. A Big Area Does Not Mean a Big Population Texas is bigger than California, making it the largest state of the 48 contiguous states, but measured by population, the rankings are reversed. California is the most populous state with  39,776,830 residents, according to 2017 U.S. Census estimates, while Texas had a population  of  28,704,330. The Lone Star State may be catching up, though, with a growth rate of 1.43 percent in 2017 compared with 0.61 percent for California. When ranked by population, Alaska drops to 48th place. Alaska  Is Larger Than the Next Three States Combined By area, Alaska is so large that it is larger than the next three states combined- Texas, California, and Montana- and is more than twice the size of second-ranked Texas. According to the State of Alaskas official website, its one-fifth the size of the lower 48 states. Alaska stretches about 2,400 miles east to west and 1,420 miles north to south. Including islands, the state has 6,640 miles of coastline (measured from point to point) and 47,300 miles of tidal shoreline.   Rhode Island Is the Smallest Rhode Island measures just 37 miles east to west and 48 miles north to south.  The states total boundary length is 160 miles. In area, Rhode Island could fit in Alaska  nearly 486 times. The next smallest state by  area  is Delaware at 2,489 square miles, followed by Connecticut, which at 5,543 square miles is more than three times the size of Rhode Island and more than twice the size of Delaware. If it were a state, the District of Columbia would be the smallest at just  68.34  square miles of which  61.05 square miles  is land and 7.29 square miles is water. Big Country West of the Mississippi The 10 largest states by area are located west of the Mississippi River:  Alaska, Texas, California, Montana, New Mexico, Arizona, Nevada, Colorado, Oregon, and Wyoming.   7 Smallest Are in the Northeast The seven smallest states- Massachusetts, Vermont, New Hampshire, New Jersey, Connecticut, Delaware, and Rhode Island- are in the Northeast and are among the 13 original colonies. The Ranking of States by Area in Square Miles This includes water features that are part of that state. Alaska - 663,267Texas - 268,580California - 163,695Montana - 147,042New Mexico - 121,589Arizona - 113,998Nevada - 110,560Colorado - 104,093Oregon - 98,380Wyoming - 97,813Michigan - 96,716Minnesota - 86,938Utah - 84,898Idaho - 83,570Kansas - 82,276Nebraska - 77,353South Dakota - 77,116Washington - 71,299North Dakota - 70,699Oklahoma - 69,898Missouri - 69,704Florida - 65,754Wisconsin - 65,497Georgia - 59,424Illinois - 57,914Iowa - 56,271New York - 54,556North Carolina - 53,818Arkansas - 53,178Alabama - 52,419Louisiana - 51,839Mississippi - 48,430Pennsylvania - 46,055Ohio - 44,824Virginia - 42,774Tennessee - 42,143Kentucky - 40,409Indiana - 36,417Maine - 35,384South Carolina - 32,020West Virginia - 24,229Maryland - 12,406Hawaii - 10,930Massachusetts - 10,554Vermont - 9,614New Hampshire - 9,349New Jersey - 8,721Connecticut - 5,543Delaware - 2,489Rhode Island - 1,545

Sunday, February 16, 2020

Mass media and communication in International Management Essay

Mass media and communication in International Management - Essay Example Some amount of imagery is associated in a language and communication and complex thoughts are communicated. According to Whorf (2011), language tends to create real and imaginary plurals and conjures up mental patterns. When an image is created or presented, some associations tend to form in the mind and create patterns of objectification. Kramsch (1998) argues that language is the main method where social lives and relations are carried out. It is used for different communication contexts and people express facts, events, ideas that are communicated through words and images. These reflect the culture, attitude and beliefs of the authors and hence language is used to express cultural reality. Therefore, language is a system of signs with a cultural value that is symbolised by social appropriateness norms and social conventions. Language, culture and social norms help people to identify themselves as members of a social group where common ways of viewing the world are acquired. In lig ht of analysing the Ad by Jamie Oliver, these associations become relevant since he is attempting to use the language of cooking to sell products to people. According to Agar (1994), words can have words have multiple meanings and these are connotative or denotative. Denotation refers to the explicit meaning and translation of the word as mentioned in a dictionary.3. DESCRIPTION OF THE ADPlease refer to figure 1.1, where the celebrity cook Jamie Oliver is showing adding vegetables and cooking a dish of chicken. Prominent in the Ad is the ad copy with the words 'Chicken. Jamie Style' and these words are expected to have multiple implications for the audience. He is shown adding leafy vegetables to a large platter containing potatoes and chicken. Another similar dish filled with chicken pieces and potatoes is placed on the right side. In the background, a cupboard is shown and the top is filled with leafy vegetables, potatoes and

Sunday, February 2, 2020

Profiling an Non Government Organization (NGO) Essay

Profiling an Non Government Organization (NGO) - Essay Example This essay describes the People for Ethical Treatment of Animals organisation (PETA), that is the largest organization in the world fighting for animal rights. PETA was founded in USA in the year 1980, by Ingrid E. Newkirk. Today, the researcher states that it has affiliates in France, Netherlands, India, United Kingdom, Germany and over 15 countries in the Asia-Pacific region. The organisation aims at the welfare of animals. It intervenes in areas where animals suffer. The mission of PETA is to focus on four key issues where animals suffer the most, including laboratories, clothing trade entertainment industry, factory farms and domesticating environments. The researcher also discusses the controversies as strategies that PETA used recently. People for Ethical Treatment of Animals have been using civil disobedience and controversies as a strategy to attain public attention and attract government interventions. For Instance, the campaigns of People for Ethical Treatment of Animals in cluded nudity. The naked campaign which began few years ago saw participation from celebrities like Pamela Anderson, Christy Turlington, Todd Oldham Marcus Schenkenberg and Kim Basinger. A very interesting public education propaganda that People for Ethical Treatment of Animals could introduce was the awareness campaigns on pet animals that was also mentioned in the essay. In conclusion, the researcher suggests challenges of the organisation, such as funding and the sustained availability of contributions.

Saturday, January 25, 2020

Urinary Excretion and Paracetamol

Urinary Excretion and Paracetamol Investigateurinary excretion of paracetamol in man. Paracetamol, known as acetaminophen in the USA, is one of the most commonly used analgesic and antipyretic drugs available over-the-counter. Its common name derives from the full chemical name: para-acetyl-amino-phenol, with the chemical formula C8H9NO2 and amolecular weight of 151.17. Paracetamol does not have anysignificant anti-inflammatory action and therefore cannot be accuratelydescribed as a non-steroidal anti-inflammatory drug (NSAID), as was oncethought. Its mechanism of action is still poorly understood but some studieshave suggested that it inhibits a variant of the cyclo-oxygenase enzyme COX-1, which has been designated COX-3 (Swierkosz et al. 2002). Paracetamol actsmainly in the central nervous system and endothelial cells, rather than inplatelets and immune cells. Boutaud and colleagues (2002) hypothesised thatthis may be explained by the high levels of peroxides found in the latter cell types, which inhibit the action of paracetamol. There has been some debate on thesubject, with other researchers proposing an inhibitory action against COX-2(Graham Scott 2005). Further research is required to fully elucidate the mechanism of action at the molecular level. Metabolism and excretion Following oral administration and absorption from the gastrointestinal tract, paracetamol enters the blood and is distributed throughout the body. It is metabolised by enzymes in the hepatocytes of the liver and the majority is converted to inactive metabolites by conjugation with sulphate or glucuronide. This is then filtered out of theblood by the kidneys and into the urine, via active renal tubular secretion. Asmall portion of paracetamol remains unaltered and passes into the urine viaglomerular filtration and passive absorption (Morris Levy 1984). Thereis also a small proportion of the paracetamol that is metabolised by the thecytochrome P450 system, which results in the formation of cysteine or glutathioneconjugates and mercapturic acid conjugates (figure 2). These products ofoxidative metabolism are also excreted renally (Andrews et al. 1976). Paracetamol has a low therapeuticindex, so the therapeutic dose is very close to the toxic dose. Toxicity canoccur following a single large dose (>10g) or with chronic lower doses(4-5g/d) and is usually seen as hepatotoxicity, which can result in deathwithin several days (Wikipedia). Toxicity occurs when the enzymesresponsible for catalysing sulphate and glucuronide conjugation becomesaturated, forcing metabolism to be increasingly dependent upon the cytochromeP450 system. This results in formation of a toxic metabolite,N-acetyl-p-benzo-quinone imine (NAPQI), which is normally mopped up by bindingto the sulphydryl group of glutathione to form inactive conjugates andmercapturic acid. Toxicity occurs when the glutathione supply becomes exhaustedand NAPQI binds indiscriminately to molecules within the cell, such asmembranes, to cause cell damage and death, seen as acute hepatic necrosis. 1)Major pathway for normal metabolism 2)Minor pathway via cytochrome P450 system produces toxic metabolite (NAPQI),shown in red. Normally this is detoxified by binding to glutathione. 3) Toxicity occurs when pathways 1 and 2 are overloadedand NAPQI binds to molecules of the cell, causing damage. Modifiedfrom Rang et al. 1995. Aim of experiment The aim of this experiment is toinvestigate the renal excretion of paracetamol, by measuring the levels ofparacetamol metabolites in human urine over 6 hours following an oral dose of500mg. The total excretion will be assessed using the spectrophotometricmethod. From this data the elimination rate constant (KE) and thehalf-life (T1/2) will be calculated. Qualitative analysis of thevarious metabolites will be conducted using appropriate chemical identificationtechniques. METHOD A standard stock solution ofparacetamol was prepared at 1mg/cm3 and dilutions were made to givea range of known concentrations. 1 cm3 of the paracetamol solutionwas added to 1 cm3 blank urine and 4 cm3 4M HCl, andmixed thoroughly. A blank duplicate was also prepared, using water instead ofurine. After an hour in a boiling water bath the tubes were cooled and wateradded, up to 10 cm3. 1 cm3 of this hydrolysed urinesolution was added to 10 cm3  of colour forming solution, mixed and allowed to stand for40 minutes. The absorbance of each solution was measured, using thespectrophotometer, zeroing the instrument using the drug free urine sample inbetween solutions. This produced the readings for the calibration curve. Thecollected timed urine samples were then processed in the same way, adding 1 cm3water instead of paracetamol solution. RESULTS AND DISCUSSION Known concentrations of paracetamolunderwent spectrophotometry to measure the absorbance at 620nm. These resultswere used to produce a calibration curve (figure 3). The timed urine sampleswere then analysed following the same protocol and the absorbance at 620nm wasused, in conjunction with the calibration curve to ascertain the concentrationof paracetamol in the urine. Unfortunately, half of the samples producedabsorbances outside the range of the calibration curve. Because this curve isnon-linear, extrapolation and dilution cannot be used to accurately deduce theconcentration of paracetamol in the urine. For the purposes of this report theconcentration for these samples has been declared as greater than 800ug/cm3.This is not very satisfactory and further experiments must be done to extendthe range of the calibration curve to the maximum absorbancy of the timedsamples. The values of KE and T1/2 have been calculatedto demonstrate the procedure, but are inaccurate and will need revisi ng onceaccurate concentrations have been established form the calibration curve. Table 1: Timed urine sample Mean absorbance 620nm Conc. ug/cm3 Vol. Urine (ml) Total drug (ug of paracetamol) Excretion rate mg/h 0 0 0 0 0 0 1 hour 0.256 192 245 47040 47 2 hours 1.918 >800 50 40000 40 3 hours 1.769 >800 38 30400 30.4 4 hours 1.028 >800 55 44000 44 5 hours 0.349 246 135 33210 33.2 6 hours 0.255 192 160 30720 30.7 Table 1 contains the absorbanceresults of the timed urine samples and the deduced concentration of paracetamolin the urine, as well as the hourly excretion rate. The total amount ofparacetamol excreted over the 6 hour period was 225.3mg, which is 45% of theorally administered dose. Due to problems discussed above, this is anunderestimate of the true percentage of dose excreted renally, which has beenfound to be 55-70% by other studies (Steventon et al. 1996). When log of the excretion rate(equivalent to total drug excreted per hour) is plotted against time, a linearplot should be achieved, from which KE can be estimated. The slope of this straight lineequates to : KE /2.303, which gives a value for KE of0.094. Using the formula: T1/2 =0.692/ KE , the valueof T1/2 = 7.36 hours. This states that it takes the body7.36 hours to excrete half of the drug administered. This is longer than the1-4 hours usually quoted for paracetamol (Rang et al. 1995), and is notsurprising given the underestimation of the paracetamol urine concentration.With proper calibration, this would be expected to decrease to nearer thepreviously found results. There were no results for thequalitative studies for metabolite composition, but it would be expected thatsulphate and glucuronide conjugates would constitute the majority of the sample,with a smaller quantity of unchanged paracetamol, cysteine/glutathione andmercapturic acid metabolites. These results only represent oneindividual on one day and replications of this experiment are crucial.Nutritional status, recent alcohol consumption, ethnic background, concurrentdrug usage and illness must all be taken into account as factors that mayaffect paracetamol metabolism and excretion (Riordan Williams 2002, Patel Tang 1992). Further analysis of paracetamolexcretion .  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Hepatotoxicity and drug interactions Table 2 shows how concurrent use of phenobarbital, ananti-epileptic drug, can increase the severity of liver damage caused byparacetamol administration and its subsequent metabolism. Table 2: Effect of Phenobarbital onparacetamol induced hepatotoxicity TreatmentDose of Paracetamol (mg/kg) Severity of liver necrosis None 375 1-2+ Phenobarbital 375 2-4+_________ This occurs due to metabolism ofphenobarbital by enzymes of the P450 cytochrome system, which results inupregulation of their production. As explained in the introduction (see fig.2), P450 enzymes also metabolise paracetamol, to form the toxic metaboliteNAPQI. This is normally a minor pathway but as the amount of P450 enzymesavailable increases, the activity of this pathway also increases. This resultsin a larger than normal amount of NAPQI, which is mopped up and inactivated byglutathione. Glutathione supplies will eventually run out, which occurs soonerif the person is malnourished. When this happens the toxic metabolite binds tocell components, causing necrosis. To prevent this occurring, such as in casesof overdose, N-acetylcysteine can be given (Routledge et al. 1998), which isrequired for glutathione synthesis and helps to boost it. This allows agreater amount of the toxic metabolite to be mopped up and reduces cell damage. .  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Paracetamol metabolism following hepatotoxicity Table 3: Plasmaparacetamol concentrations(ug/cm3) Patients Plasma paracetamol 4 hrs after 12hrsafter Half life (h) ingestion ingestion _______________________________________________________________ noliver damage (18) 2.9 +/= 0.3 163 +/=20 29.5 +/=6 liverdamage (23) 7.2+/= 0.7 296 +/= 26 124 +/=22___ Table 3 shows that, in a study, theability of patients with liver damage to eliminate paracetamol from the bloodis much decreased, compared to healthy people. This is seen by the prolongedhalf-life and the high levels of paracetamol in the plasma. The plasma leveldoes come down by 12 hrs, which indicates that there is enough functional liverreserve to metabolise some of the drug, but the level is still very high. Toascertain whether it is just conjugation that is affected, or whether all thepathways are affected equally it would be necessary to quantify the levels ofdifferent metabolites in the blood and urine. As conjugation is responsiblefor the majority of metabolism, damage to all systems will still show up asaffecting conjugation the most. In theory reduced clearance of asubstance is useful for monitoring the severity of liver damage, but in thecase of paracetamol it would be unwise as it could potentiate the hepatotoxiceffects and worsen the liver condition. It is also unnecessary as there arealready a number of reliable blood tests for liver function and damage. REFERENCES Andrews, R. S., Bond, C. C., Burnett, J., Saunders, A. Watson, K. 1976 Isolation and identification of paracetamol metabolites. J Int Med Res 4,34-9. Boutaud, O., Aronoff, D. M., Richardson, J. H., Marnett, L. J. Oates, J. A. 2002 Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases. Proc Natl Acad Sci U S A 99,7130-5. Graham, G. G. Scott, K. F. 2005 Mechanism of action of paracetamol. Am J Ther 12, 46-55. Morris, M. E. Levy, G. 1984 Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans. J Pharm Sci 73, 1038-41. Patel, M., Tang, B. K. Kalow, W. 1992 Variability of acetaminophen metabolism in Caucasians and Orientals. Pharmacogenetics 2, 38-45. Rang, H. P., Dale, M.M., Ritter, J.M. 1995 Pharmacology: Churchill Livingstone. Riordan, S. M. Williams, R. 2002 Alcohol exposure and paracetamol-induced hepatotoxicity. Addict Biol 7, 191-206. Routledge, P., Vale, J. A., Bateman, D. N., Johnston, G. D., Jones, A., Judd, A., Thomas, S., Volans, G., Prescott, L. F. Proudfoot, A. 1998 Paracetamol (acetaminophen) poisoning. No need to change current guidelines to accident departments. Bmj 317, 1609-10. Steventon, G. B., Mitchell, S. C. Waring, R. H. 1996 Human metabolism of paracetamol (acetaminophen) at different dose levels. Drug Metabol Drug Interact 13, 111-7. Swierkosz, T. A., Jordan, L., McBride, M., McGough, K., Devlin, J. Botting, R. M. 2002 Actions of paracetamol on cyclooxygenases in tissue and cell homogenates of mouse and rabbit. Med Sci Monit 8, BR496-503. http://en.wikipedia.org/wiki/Paracetamol.

Friday, January 17, 2020

A Comparative Analysis of Devlin and Mill Essay

It can be assumed that if J.S. Mill and Lord Devlin ever coexisted some intoxicating deliberations regarding the role of morality in society would transpire. However, time has a peculiar habit of erecting boundaries amid centuries, allowing us only to presume discourse between the contemporary and the historical. Consequentially, each individual has an obligation to formulate his or her own appraisal established through the logistic unification of the particular instant and one’s own conception of idealistic righteousness. But the acquisition of an infallible and tangible philosophy with universal application would be as obstinate to create as it would to fathom. In such regard, the apparatus on which debate must rest is well constructed. If each were to believe in the intricate purity of his inspiration than no philosophy but his own would be received. It is subsequently the responsibility of that creature to sell his faculty, ensuing the continued survival of dispute. It is the function of this formula to patiently arrive at a conciliated truth in which the majority of a society can divulge. If the perceived truth were to have an impact on the thirst and fertility of an entire society than it would be in that institution’s interest to create a fountain from which everyone could drink. It is this motive that has justifiably birthed meticulous curiosity in the works of both Lord Devlin and John Stuart Mill, each of whom have crafted disparate cures for the perils of harm in society, but neither of whom have succeeded in absorbing the values of the other. However, to adequately dissect values there must first be an ample understanding of the beliefs of each party concerned, only then can one interpret the mutual ethics from the personal. Mill perceives only one instance in which society is justified in interfering with or limiting the freedoms of its adult members, that being to prevent harm to others. Though Mill would also claim that not all harm could rationalize intruding on an individual’s freedom, the harm must overshadow the liberty being reduced. Additionally, Mill introduces two forms of harm, direct and indirect. Direct harm occurs when the actions of one member of a society has a negative impact on another as a result of that individuals  behavior. Consequently, Mill would argue that a mugger has had a direct harm on his victim because the outcome of the event was immediate and detrimental. Indirect harm is habitually tolerable because most acts can affect others; accordingly, if the act has a detrimental effect on others but only as being consequential of the affect of the individual on himself, it is justifiable. For instance, if a man chooses to remain in ill health rather than obtain appropriate medical assistance, he is detrimental to society, but only as a result of him harming himself. This is distinguishable as indirectly harmful because there was an intermediate source of the harm, that being the man’s preference. Contrary to Mill, Devlin would categorize this form of indirect harm as immoral and injurious to society as a whole. While Mill argues that harmless actions, such as a man choosing ill health rather than being a productive member of a society must not be the subject of social coercion, Devlin would assert that the harmless action is in actuality damaging societies moral composition, requiring it to be made the subject of social control. Stressed by Devlin is the belief that â€Å"†¦there are certain standards of behavior or moral principles which society requires to be observed; and the breach of them is an offense not merely against the person who is injured but against society as a whole.† In context we find the incongruity. Mill approaches the permissibility of regulating personal liberties only as an edict to preventing harm, never consenting to use the regulation of liberty to enforce morals. In contrast, Devlin’s tactic is to implement a moral principle to help protect society from itself, trusting that without this principle there would be social disintegration. Moreover Devlin asserts that moral legislation is crucial to maintain a social bond. He maintains that society has a right to protect its own existence by barring behavior that threatens that existence. This is distinctly divergent from Mill’s perceptions on paternalism. Mill claimed that there must be unconditional rejection of paternalism by the state, only invalidated to prevent persons from selling themselves into slavery. Reinforcing his case Mill argued that paternalistic intervention is unlikely to work because an individual is acutely more aware of his or her own needs than the state is. Additionally, he argued that it is improbable  compulsion would work. This can also be taken into account in the form of liberty. Mill alleges that an autonomous life has more value than a life of dependency, since one cannot be forced to be autonomous paternalism has a damaging effect on an individual. As a contemporarily relevant issue, Devlin indirectly delivers his rebuttal to paternalism by embodying a stance on homosexuality. He defends societies right to protect its own existence by vetoing behavior that threatens its sustainability, since homosexuality is detrimental to society that union has a right to prohibit it. This is consistent with Devlin’s definition of â€Å"tangible harm†, described as a harm that instigates a diminution of the physical strength of society. When practiced in trivial quantities these activities can be harmless, however as its participants grow it has a linear effect on its harm. In accordance, he also argues that â€Å"unrestricted indulgence in vice† will weaken an individual to the extent that he ceases to be a useful member of society and society itself will deteriorate in the event that a sufficient number of its members are plagued by vice. However, the tangible harm that certain forms of conduct allegedly cause is restricted to the applicability of that behavior’s breach to the shared morality. If homosexuality is injurious to society it is so regardless of whether it violates the shared morality or not. In conjunction with this notion, Mill would affix his fundamental belief that this individual’s decision to practice homosexua lity is impartial because it is a sovereign decision. Mill asserts, â€Å"If a person possess a tolerable amount of common sense and experience, his own mode of laying out his existence is the best, not because it is the best in itself but because it is his own mode.† Likewise, if it is generally believed that sexual immorality will effectively cause the collapse of a society there may be validation for suppressing this deviant conduct but individual freedom prevents us from accepting this. If the repression of seemingly deviant acts were the norm there would exist an agency to justify intolerances founded on, among many others, religion and race. Mill would also note that it allocates a leeway to repressing self-regarding actions, which include liberty of conscience and expression, tastes and pursuits and liberty of association. Besides the value of the self-regarding sphere, Mill stresses the importance of freedom of expression, which in proviso to Devlin, is capable in itself of tugging at the societal nit. Devlin has suggested that society is a culturally elastic entity that persists through various changes in social mores, owing to his elastic principles it can be argued that he has a general tolerance for individual freedom. However, he rejects Mill’s perception of freedom on the basis that he has an idealistic picture of human beings. He professes that Mill holds an earnest view of an individual conscientiously doing what he thinks is right regardless of the acceptance of his behavior. This is easily categorized as Mill’s claim to freedom of expression. According to Mill, opinions or beliefs cannot be suppressed for the reason that they are among other things immoral or shocking, the only validity for suppression is if they are harmful. As Devlin has claimed, â€Å"†¦freedom of action follows naturally on [freedom of expression]; men must be allowed to do what they are allowed to talk about doing†¦what Mill visualizes is people doing things he himself would disapprove of, but doing them earnestly and openly and after thought and discussion†¦This seems to me on the whole an idealistic picture.† But Devlin believes this is seldom true of those who violate the shared morality of society. He believes that most individuals acknowledge the fallibility of their conduct but continue it for lust and money. He believes, â€Å"Freedom to do what you know to be bad is worthless.† However, a person may breach the values of his society with the belief that those morals are not intrinsic and encompass various modes of conduct that he believes are morally permissible. If the action does not harm others the liberty to pursue ones own tastes and pursuits should be boundless. By this notion, vices are only such if they are acknowledged by those who engage in them. Mill reinforces his conviction against censorship by indicating that a censored opinion might be true, or if it is literally false may contain part of the truth, additionally, if it is entirely false, a censored opinion would prevent true opinions from becoming dogma and as a dogma an unchallenged truth will lose its meaning. An individual, as mentioned by Mill, is more inclined to pursue personal righteousness with unlimited access to the truth, which requires freedom of expression. As Devlin would concede, the pursuit of individual infallibility would coincide with the aspiration of a morally entrenched society. Although Devlin has the benefit of criticizing Mill’s assertions without the risk of rebuttal he has yet to disprove the accuracy of Mill’s libertarian approach. Devlin’s disputes address a number of Mill’s themes, including his harm principle, paternalism and freedom of expression, but fail to yield an internalized acceptance of their circular approach to discrediting one of philosophies nobles. Furthermore, Devlin’s disintegration thesis attempts to secede harm to society from harm to individuals, as such, his appeal to the concept of gross social injury could be viewed as an application of a public harm principle. As such, the cumulative effect of harm on a collective group of individuals has the capacity to cause a disturbance in public interest. Consequently, the incongruity between Mill and Devlin can be reduced to the acceptance that Mill embraces both public and private harm, while Devlin incorporates a deviant version of private impairment and a similar notion of public hurt. If, then, the claims made by Devlin are accurate, it can also be argued that Mill would support the legal enforcement of shared morality. As of yet society still covets the search for a public fountain, probing our faculties for the cure to all our vices, but refusing to accept the likelihood that there may never be enough water to satisfy every persons thirst.

Thursday, January 9, 2020

Mythological References in Hamlet Essay - 1313 Words

Mythological References in Hamlet Whats in a name? Hamlets good friend and confidant Horatio is doomed by the etymology of his nomenclature to give good speech. Shakespeare has gifted Horatio with an elegant lucidty that, when inspected closely, enables the reader to better comprehend the nature of the play; one of his first addresses is key in setting the tone of what James Joyce called the grave and constant in human suffering (Campbell 8). This is also a principal theme of classical mythology, and to fully understand Hamlet as a tragic hero, a comprehension of the mythological references at the beginning of the play must be foremost in the readers mind. These metaphoric intimations of tragedy; leaked in Hamlets and†¦show more content†¦(I.i.ll7-24) A fascinating event like an eclipse was used to explain away strange behavior or portend odd goings-on. It is believed that Hamlet was written no earlier than 1598. Around this time, Copernicus concept of a heliocentric universe was gaining strong popularity. It is possible that Shakespeare might have been influenced by this idea; since he play is thought to be set around 1200, it is more likely that a subconscious consignment of information passed from Shakespeares pen into Horatios intellect. With a potential new perception of how the sun and moon and earth move in their orbits and how those movements affect things like the tides, Horatio might have equated this with motions and circumstances affecting people and sets up his metaphor to perform a double duty. One, he views the visitation of King Hamlets host as precurse to fierce events, almost like the calm before the storm(within Neptunes empire). Something bad is going to happen: anytime you see a ghost it is usually bad news. T wo, he uses the phrase Disasters in the sun as a kind of prologue-like epithet for Hamlets light and to express the magnitude of the omen coming on. 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